Product Information
- 2,4(1H,3H)-Pyrimidinedione, 5-amino-6-methyl-
- 5-Amino-6-methyl-2,4(1H,3H)-pyrimidinedione
- 5-amino-6-methylpyrimidine-2,4(1H,3H)-dione
- NSC 35527
- Uracil, 5-amino-6-methyl-
- 5-Amino-6-methyluracil
5-Amino-6-methyl-pyrimidine-2,4-diol is a tautomer of 5-Aminouracil. It is an antiradical agent that has been shown to have hydroxyl radical scavenging activity in the presence of peroxide. The mechanism of the reaction involves the formation of a hydrated form of 5-amino-6-methylpyrimidine 2,4-diol, which reacts with the peroxide to form a stable product. The hydration step is required for this reaction to occur and may be rate limiting. The measurements obtained from nmr spectra are consistent with this mechanism. 5 aminouracil has been shown to inhibit growth and DNA synthesis in tumor cells in vitro.
Chemical properties
Technical inquiry about: 3D-GAA27046 5-Amino-6-methyl-pyrimidine-2,4-diol
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