5-Methoxynaphthalen-1-amine
CAS: 6271-81-4
Ref. 3D-GAA27181
| 1g | Discontinued | ||
| 5g | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
5-Methoxynaphthalen-1-amine
Synonyms:
- 5-Methoxy-1-naphthalenamine
- 1-Naphthylamine, 5-methoxy-
- 5-Methoxy-1-naphthylamine
- 1-Amino-5-methoxynaphthalene
- 1-Naphthalenamine, 5-methoxy-
Description:
5-Methoxynaphthalen-1-amine is a ligand for the P-gp efflux pump. It has been shown to have high affinity for this protein, with a Kd of 0.4 nM. This drug also has an optical rotation of [α]D=−5.5° and can be used as a diagnostic ligand in positron emission tomography (PET) imaging studies. 5-Methoxynaphthalen-1-amine can be used to identify binding sites for the P-gp efflux pump, which is often expressed at low levels on tumor cells and is important in promoting resistance to chemotherapeutic drugs.
5-Methoxynaphthalen-1-amine is also a chiral compound that can bind to the receptor subtype P2X7, potentially providing new insights into how these receptors contribute to inflammation and pain pathways.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
173.21 g/mol
Formula:
C11H11NO
Purity:
Min. 95%
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