1-Ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS: 6490-42-2
Ref. 3D-GAA49042
| 1g | 1,023.00 € | ||
| 100mg | 257.00 € |
Product Information
1-Ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (ETP) is a potent inhibitor of pyrimidine biosynthesis. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. ETP binds to the enzyme dihydroorotate dehydrogenase and prevents the formation of orotic acid from l-tartaric acid. This inhibition leads to an accumulation of orotic acid and l-tartaric acid in the cell which inhibits cellular respiration. ETP also inhibits other enzymes involved in DNA replication, such as ribonucleotide reductase and thymidylate synthase. This inhibition leads to decreased synthesis of DNA and RNA molecules that are necessary for cell division. ETP has also been shown to be effective against hepatitis B virus by inhibiting viral DNA synthesis and causing viral DNA degradation.
Chemical properties
Technical inquiry about: 3D-GAA49042 1-Ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
