6,7-Dimethoxy-1H-indole
CAS: 31165-13-6
Ref. 3D-GBA16513
1g | Discontinued | ||
50mg | Discontinued | ||
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
- 1H-indole, 6,7-dimethoxy-
6,7-Dimethoxy-1H-indole is a primary amine that has been shown to inhibit the function of integrase, an enzyme that is involved in viral replication. It also has anti-fungal and antiviral properties and can be used as a potential treatment for cancer. 6,7-Dimethoxy-1H-indole binds to the integrase active site with high affinity and inhibits its activity. The compound was found to be potent against several tumor cell lines in vitro. It also has antibiotic activity against some bacteria by binding to the enzyme DNA gyrase, which is involved in bacterial DNA replication. This compound was found to have a disubstitution pattern in its molecular modeling that differs from other substituted indoles. The different substitutions may contribute to its pharmacophore and potent antitumor activity.