Product Information
2,2,5,6-Tetramethyl-2,3-dihydropyrazine (TMPD) is a chemical compound that inhibits the enzyme that catalyzes the reaction of vitamin K with glutamate to form clotting factors II, VII, IX and X. TMPD is metabolized by rat liver microsomes to 2-amino-4,6-dinitrophenol (DNP). The DNP then reacts with glutathione to produce a toxic product. TMPD has been shown to have anticoagulant effects in rats and is used as an experimental drug for leukemia treatment. TMPD also inhibits microbial growth by acting as a competitive inhibitor of microbial metabolism. This chemical can be found in food items such as caproic acid and has been detected in basophilic leukemia cells.
Chemical properties
Technical inquiry about: 3D-GBA83961 2,2,5,6-Tetramethyl-2,3-dihydropyrazine
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