Methyl 4-amino-5-methylthiophene-3-carboxylate
CAS: 81528-48-5
Ref. 3D-GDA52848
| 250mg | 229.00 € | ||
| 2500mg | 894.00 € |
Product Information
Methyl 4-amino-5-methylthiophene-3-carboxylate (AMTC) is a synthetic inhibitor of the enzyme acetyl-coa carboxylase. AMTC is used as a research tool to study the role of acetyl-coa carboxylase in plants and animals. In Arabidopsis, AMTC inhibits the synthesis of fatty acids, leading to reduced seed oil content. It also inhibits transcarboxylase in wheat, which causes an accumulation of acetate. AMTC is synthesized by reacting methyl 4-nitrobenzoate with thieno[2,3,-c]pyrazole in the presence of palladium(II) chloride and potassium carbonate. The product undergoes hydrogenation to give AMTC.
Chemical properties
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