mGluR5 Ligand, CDPPB

CAS: 781652-57-1

Ref. 3D-GGB65257

Product Information

• Name: mGluR5 Ligand, CDPPB
• Synonyms: 3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide, 3-Cyano-N-(2,5-diphenylpyrazol-3-yl)benzamide, Benzamide, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)-, Cdppb
• CAS: 781652-57-1

Description

CDPPB is a potent, selective, and orally active mGluR5 ligand. It has been shown to inhibit the activation of cell signaling pathways that are involved in dopamine release and glutamate-mediated synaptic transmission. CDPPB is characterized by allosteric activity, which means that it binds to the metabotropic glutamate receptor (mGluR) and alters its function. This drug also inhibits protein synthesis and increases locomotor activity in mice. CDPPB has been studied as a possible treatment for skin cancer and may have therapeutic potential for other diseases of the central nervous system such as Parkinson's disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 364.4 g/mol
• Formula: C₂₃H₁₆N₄O
• Purity: Min. 95%