![(4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one](https://static.cymitquimica.com/products/3D/img/GHD26142.png "Click to enlarge")
(4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one
CAS: 2056261-42-6
Ref. 3D-GHD26142
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one (EDQ) is a potent inhibitor of the voltage dependent ion channels. It has been shown to be an effective inhibitor of the Na+ and Ca2+ channels in mammalian cells. EDQ binds to the extracellular loops of these channels and inhibits their function by blocking the opening of the channel pore. The inhibition of these ion channels leads to a decrease in neurotransmitter release and prevents neuronal depolarization. This compound can be used as a research tool for studying cell biology, peptides, pharmacology and ligands. It is also used as a reagent for testing receptor activation with high purity.
Chemical properties
Technical inquiry about: 3D-GHD26142 (4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one
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