Product Information
- 1-(Brommethyl)-3,5-dichlorbenzol
- 1-(Bromomethyl)-3,5-dichlorobenzene
- Benzene, 1-(bromomethyl)-3,5-dichloro-
5-(Bromomethyl)-1,3-dichlorobenzene is a lead compound for the treatment of osteoarthritis. It inhibits aggrecanase and proteoglycanases, which are enzymes that break down proteins in cartilage. 5-(Bromomethyl)-1,3-dichlorobenzene has been shown to inhibit mmp-1 and tnf-α and to be selective for aggrecanase over other proteoglycanases. This drug also has anti-inflammatory properties due to its ability to inhibit cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 5-(Bromomethyl)-1,3-dichlorobenzene is a racemic mixture of two enantiomers (enantiomer 1 and enantiomer 2). Enantiomer 1 is more potent than enantiomer 2 at inhibiting aggrecanase and proteoglycanases.
Chemical properties
Technical inquiry about: 3D-HAA77801 5-(Bromomethyl)-1,3-dichlorobenzene
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