Ergosta-7,22-dien-3-one
CAS: 32507-77-0
Ref. 3D-HBA50777
1mg | To inquire | |
2mg | To inquire | |
5mg | To inquire | |
10mg | To inquire | |
25mg | To inquire |
Product Information
Ergosta-7,22-dien-3-one is a novel compound isolated from the mycelium of Ganoderma lucidum. It inhibits transcriptional activity of the DNA polymerase chain reaction and has been shown to have inhibitory effects on neutrophil chemotaxis. Ergosta-7,22-dien-3-one has been found to have anticancer and antiinflammatory bioactivities. A coriolus extract (CE) has been shown to inhibit the growth of cancer cells with an IC50 value of 0.5 mg/mL. CE also inhibited inflammatory responses in macrophages through inhibition of NFκB activation, which was induced by lipopolysaccharide stimulation. This inhibition was partially dependent on the inhibition of protein synthesis by CE and was not seen when CE was administered at a high concentration for 48 hours. These findings suggest that CE may be a potential therapeutic agent for inflammation and cancer treatment.
Chemical properties
Technical inquiry about: 3D-HBA50777 Ergosta-7,22-dien-3-one
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.