NPPB

CAS: 107254-86-4

Ref. 3D-HEA25486

Product Information

• Name: NPPB
• Synonyms: 5-Nitro-2-[(3-Phenylpropyl)Amino]Benzoic Acid, Benzoic acid, 5-nitro-2-[(3-phenylpropyl)amino]-, Hoe 144, Hoechst 144, Nppb
• CAS: 107254-86-4

Description

NPPB is a polymeric cation channel that is activated by cytosolic Ca2+ and regulates the membrane potential of cells. It has been shown to be involved in the regulation of energy metabolism, chloride transport, and cancer cell growth. NPPB also plays an important role in neuronal death, as it can activate pro-apoptotic protein channels and regulate the release of intracellular calcium. NPPB is found predominantly in the apical region of mitochondria membranes, but can also be found in other locations such as the plasma membrane. It is regulated by oxidative injury and changes in mitochondrial membrane potential.

• Brand: Biosynth

Chemical properties

• Molecular weight: 300.31 g/mol
• Formula: C₁₆H₁₆N₂O₄
• Purity: Min. 95%