Acyclovir acetate

CAS: 102728-64-3

Ref. 3D-IA17213

Product Information

• Name: Acyclovir acetate
• Synonyms: 9-[[2-(Acetyloxy)ethoxy]methyl]-2-amino-1,9-dihydro-6H-purin-6-one9-(2-Acetoxyethoxymethyl)guanineAcyclovir Impurity A, 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate, 6H-purin-6-one, 9-[[2-(acetyloxy)ethoxy]methyl]-2-amino-1,9-dihydro-, 2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate
• CAS: 102728-64-3

Description

Acyclovir is an antiviral agent that prevents the growth of herpes simplex virus. Acyclovir is a prodrug, which is converted to acycloguanosine 5'-triphosphate (ACV-TP) in vivo. ACV-TP inhibits viral DNA polymerase and thereby prevents viral genome replication, replication. The molecular structure of Acyclovir was determined by X-ray crystallography at 3.2 Å resolution. It has been shown that ACV-TP can be activated by chloride ions and it has been suggested that this activation may be the result of an interaction with a ligand.
ACV-TP binds to guanine residues in the DNA chain and prevents the formation of hydrogen bonds between guanine and adenine or cytosine residues in the same chain, preventing DNA replication.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.24 g/mol
• Formula: C₁₀H₁₃N₅O₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C10H13N5O4/c1-6(16)19-3-2-18-5-15-4-12-7-8(15)13-10(11)14-9(7)17/h4H,2-3,5H2,1H3,(H3,11,13,14,17)
• InChI key: InChIKey=DMHAXLGAKQREIL-UHFFFAOYSA-N
• SMILES: CC(=O)OCCOCn1cnc2c(=O)[nH]c(N)nc21