N-[4-Amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]-(R,S)-2-hydroxy-2-methylpropanamide
CAS: 945419-64-7
Ref. 3D-IA58276
2mg | 144.00 € | ||
5mg | 217.00 € | ||
10mg | 325.00 € | ||
25mg | 452.00 € | ||
50mg | 633.00 € |
Product Information
- 4-Amide-3-trifluoromethyl-N-(3-p-fluorophenylsulfinyl-(R,S)-2-hydroxy-2-methylpropionyl)anilineBicalutamide sulfoxideN-[4-Cyano-3- (trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamideBicalutamide Impurity A
N-[4-Amino-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]- (R,S)-2-hydroxy-2-methylpropanamide is a sulfoxide that was designed to inhibit cancer cell proliferation. It has been shown to have anticancer activity in different models. The synthesis of this compound begins with the chlorination of 4-aminophenol, which produces 4-(chloromethyl)benzenesulfonyl chloride. This is then reacted with (R,S)-α-(4-Fluorophenyl)acetic acid and the resulting product is purified by column chromatography to give N-[4-(chloromethyl)phenyl]-3-[(4-fluorophenyl)(R,S)-sulphinyl]propaneamide. The final step in the synthesis is achieved by reacting the amide
Chemical properties
Technical inquiry about: 3D-IA58276 N-[4-Amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]-(R,S)-2-hydroxy-2-methylpropanamide
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