Dihydroergotoxine mesylate

CAS: 8067-24-1

Ref. 3D-IAA06724

Product Information

• Name: Dihydroergotoxine mesylate
• Synonyms: (5'Alpha,10Alpha)-12'-Hydroxy-3',6',18-Trioxo-2',5'-Di(Propan-2-Yl)-9,10-Dihydroergotaman Methanesulfonate (1:1), 12'-Hydroxy-5'-(2-Methylbutan-2-Yl)-3',6',18-Trioxo-2'-(Propan-2-Yl)-9,10-Dihydroergotaman, 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotoxine deriv., Alkergot, Cck 179, Circanol, Co-dercrine mesylate, Co-dergocrine mesylate, Codergine mesylate, Codergocrine methanesulfonate, Coristin, Dacoren, Deapril, Deapril ST, Decril, Dihydroergotoxin mesylate, Dihydroergotoxin methanesulfonate, Dihydroergotoxine Mesilate, Dihydroergotoxine Monomethanesulphonate, Dihydroergotoxine methanesulfonate, Dulcion, Ergodesit, Ergohydrin, Ergoloid Mesylate, Ergoplus, Ergotoxine, dihydro-, methanesulfonate (1:1), Ergotoxine, dihydro-, monomethanesulfonate (salt), Gerimal, Hydergin, Hydergine, Hydergyne, Indolo[4,3-fg]quinoline, ergotoxine deriv., Ischelium, Novofluen, Orphol, Perenan, Progeril, Redergin, Sponsin, Trigot
• CAS: 8067-24-1

Description

Dihydroergotoxine mesylate is a prodrug that is metabolized to the active form, dihydroergotoxine (DHE), which has been shown to be effective in treating heart tissue disorders and metabolic disorders. DHE inhibits the production of polyunsaturated fatty acids, which are important for maintaining healthy levels of cholesterol. It also blocks receptors for nerve growth factor (NGF), leading to neuronal death. The gene encoding NGF is found in neurons and a model system has been developed to study this effect. Symptoms of DHE-induced neuronal death in prostate cancer cells include decreased cell proliferation, increased apoptosis, and increased necrosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 2,314.74 g/mol
• Formula: C₁₂₃H₁₅₆N₂₀O₂₃S
• Purity: Min. 95%