Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide

CAS: 129083-44-9

Ref. 3D-IB58076

Product Information

• Name: Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
• Synonyms: N,N''-[dithiobis(methylene-4,2-thiazolediyl)]bis-guanidineFamotidine impurity EBis[(2-guanidino-4-thiazolyl)methyl]disulfideBis[( (2-guanidino)-4-thiazolyl)methyl]disulfide

Description

Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide is a disulfide derivative of famotidine. It has been used as an analytical reagent for the determination of impurities in famotidine and other related compounds. Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide is soluble in methanol, ethanol and water, but not in acetone. The compound can be prepared by reacting 4-(dimethylamino)-1H-1,2,3-benzothiadiazole with 2-[(diaminomethylene)amino]-4-(N'-methoxycarbonylthio)benzaldehyde and then reductive amination with sodium bisulfite.

• Brand: Biosynth

Chemical properties

• Molecular weight: 374.54 g/mol
• Formula: C₁₀H₁₄N₈S₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H14N8S4/c11-7(12)17-9-15-5(1-19-9)3-21-22-4-6-2-20-10(16-6)18-8(13)14/h1-2H,3-4H2,(H4,11,12,15,17)(H4,13,14,16,18)
• InChI key: InChIKey=ZWHJVLVEEDAPHN-UHFFFAOYSA-N
• SMILES: NC(N)=Nc1nc(CSSCc2csc(N=C(N)N)n2)cs1