8-Chloro-2H-chromen-2-one
CAS: 33491-29-1
Ref. 3D-IBA49129
1g | To inquire | ||
5g | To inquire | ||
10g | To inquire | ||
250mg | To inquire | ||
500mg | To inquire |
Product Information
8-Chloro-2H-chromen-2-one is a small molecule that acts as a protein kinase inhibitor. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo, including mammary cancer cells and cervical cancer cells. 8-Chloro-2H-chromen-2-one inhibits the tumorigenic properties of mcf-7 cells by blocking mitogenic signaling pathways, specifically the phosphorylation of pRb by protein kinase B (PKB). This compound also has antitumor activity against both cultured cell lines and xenografts, inhibiting tumor growth in nude mice.
Chemical properties
Technical inquiry about: 3D-IBA49129 8-Chloro-2H-chromen-2-one
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