Cimetidine

CAS: 51481-61-9

Ref. 3D-IC58191

Product Information

• Name: Cimetidine
• Synonyms: AcibilinAcinilN''-Cyano-N-methyl-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidineSKF-92334, 1-Cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine, 2-Cyano-1-Methyl-3-(2-(((5-Methylimidazol-4-Yl)Methyl)Thio)Ethyl)Guanidine, Acibilin, Acinil, Biomet, Cimal, Cimetag, Cimetidin, Cimetidina, Cimetidine (base or and unspecifieds salts), Cimetidine A, Cimetidine AB, Cimetum, Dyspamet, Edalene, Eureceptor, Fremet, Gastromet, Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-, Guanidine, N-cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-, Histodil, N-Cyano-N'-methyl-N''-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine, N-Cyano-N′′-methyl-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine, Nsc 335308, Peptol, Skf 92334, Tagamet, Tagamet HB, Tagamet HB 200, Tamagret, Tametin, Tratul, Ulcedin, Ulcedine, Ulcerex, Ulcerfen, Ulcimet, Ulcofalk, Ulcomedina, Ulcomet, Ulhys
• CAS: 51481-61-9

Description

Cimetidine is a histamine-2 receptor antagonist that inhibits gastric acid secretion and reduces the activity of stomach enzymes. It is used to treat peptic ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Cimetidine has been shown to inhibit the activity of drug-metabolizing enzymes such as cytochrome P450. Cimetidine also inhibits the transport protein P-glycoprotein (P-gp), which leads to increased concentrations of some drugs in the blood and tissues. This inhibition may lead to an increase in cardiac effects with certain drugs, such as x-ray diffraction data with taxol or h1 antagonists.

• Brand: Biosynth

Chemical properties

• Molecular weight: 252.34 g/mol
• Formula: C₁₀H₁₆N₆S
• Purity: Min. 95%
• Color/Form: White Powder
• SMILES: C/N=C(/NC#N)NCCSCc1nc[nH]c1C