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N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:
Ref. 3D-IC58274
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Product Information
Name:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
Synonyms:
- N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxideBicalutamide epoxide impurity
Brand:Biosynth
Description:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.
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Chemical properties
Molecular weight:270.21 g/mol
Formula:C12H9F3N2O2
Purity:Min. 95%
Color/Form:White Powder
SMILES:CC1(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)CO1
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