Demethylpiperazinyl Sildenafil Sulfonic Acid

CAS: 1357931-55-5

Ref. 3D-ID166407

Product Information

• Name: Demethylpiperazinyl Sildenafil Sulfonic Acid
• Synonyms: Sildenafil EP Impurity D
• CAS: 1357931-55-5

Description

Demethylpiperazinyl Sildenafil Sulfonic Acid is a prodrug of sildenafil, which is an organic compound. It is used in the treatment of erectile dysfunction and pulmonary arterial hypertension. This drug is metabolized by hydrolysis to form sildenafil citrate, which then acts as an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5). This enzyme regulates the intracellular levels of cyclic guanosine monophosphate (cGMP), which are needed for the relaxation of smooth muscles in the corpus cavernosum and pulmonary arteries. Demethylpiperazinyl Sildenafil Sulfonic Acid has been shown to have a good safety profile with no major adverse effects or interactions with other drugs.

• Brand: Biosynth

Chemical properties

• Molecular weight: 392.43 g/mol
• Formula: C₁₇H₂₀N₄O₅S
• Purity: Min. 95%
• InChI: InChI=1S/C17H20N4O5S/c1-4-6-12-14-15(21(3)20-12)17(22)19-16(18-14)11-9-10(27(23,24)25)7-8-13(11)26-5-2/h7-9H,4-6H2,1-3H3,(H,18,19,22)(H,23,24,25)
• InChI key: InChIKey=DFABUTFBIDMPKZ-UHFFFAOYSA-N
• SMILES: CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)O)ccc3OCC)nc12