O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt

CAS: 83373-60-8

Ref. 3D-IDA37360

Product Information

• Name: O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt
• Synonyms: Carbonodithioic acid, O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt, Carbonodithioic acid, O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt (1:1), D 609, O-(Octahydro-4,7-methano-1H-inden-5-yl)carbonodithioate potassium salt, O-(octahydro-1H-4,7-methanoinden-5-yl) hydrogen carbonodithioate, Potassium O-(octahydro-4,7-methano-1H-inden-5-yl) carbonodithioate (1:1), Tricyclo-decan-9-yl-xanthate, Tricyclodecane-9-yl-xanthogenate, potassium O-(octahydro-1H-4,7-methanoinden-5-yl) dithiocarbonate

Description

O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt (OTCDK) is a cytosolic calcium ionophore that activates soluble guanylate cyclase (sGC). This activation leads to an increase in intracellular levels of cGMP and thereby the production of nitric oxide (NO). OTCDK has been shown to inhibit the synthesis of prostanoids by inhibiting the activity of enzymes such as phospholipase A2 and COX-2 that are responsible for the conversion of arachidonic acid to prostaglandins. This drug also inhibits bladder contractility and relaxes muscle, which may be due to its ability to inhibit calcium influx into cells. OTCDK has been shown to induce relaxation in isolated arteries and reduce atherosclerotic lesion size in mice. The concentration-response curve for OTCDK was found to be steepest

• Brand: Biosynth

Chemical properties

• Molecular weight: 266.46 g/mol
• Formula: C₁₁H₁₅KOS₂
• Purity: Min. 95%