Enalapril maleate impurity C

CAS: 76420-72-9

Ref. 3D-IE63755

Product Information

• Name: Enalapril maleate impurity C
• Synonyms: N-[1(S)-Carboxy-3-phenylpropyl]-L-alanyl-L-prolineEnalaprilat, (2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, <span class="text-smallcaps">L</smallcap>-Proline, 1-[N-(1-carboxy-3-phenylpropyl)-<smallcap>L</span>-alanyl]-, (S)-, <span class="text-smallcaps">L</smallcap>-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-<smallcap>L</span>-alanyl-, Enalapril acid, Enalapril diacid, Enalaprilat Hydrate, Enalaprilat Usp(Crm Standard), Enalaprilate, Enalaprilic Acid, MK 421 diacid, Mk 422, N-[(1S)-1-(Carboxy)-3-phenylpropyl]-L-alanyl]-L-proline Dihydrate, N-[(1S)-1-Carboxy-3-phenylpropyl]-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</span>-proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline, N-[1(S)-Carboxy-3-phenylpropyl]-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</span>-proline, N-[1(S)-Carboxy-3-phenylpropyl]-L-alanyl-L-proline, Vasotec IV, L-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-, L-Proline, 1-[N-(1-carboxy-3-phenylpropyl)-L-alanyl]-, (S)-

Description

Enalapril maleate impurity C (E-C) is an impurity of enalapril, a drug that inhibits angiotensin-converting enzyme. It has been shown to have antihypertensive activity in animals and humans. Enalapril maleate impurity C is found in wastewater and may be used as a marker for the presence of enalapril. The bioavailability of enalaprilat, which has been shown to have similar pharmacokinetics to captopril, can be determined by measuring the plasma concentrations of E-C in blood samples. This analytical method is useful for determining whether two drugs are bioequivalent.

• Brand: Biosynth

Chemical properties

• Molecular weight: 348.39 g/mol
• Formula: C₁₈H₂₄N₂O₅
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder