Fluticasone propionate EP Impurity F

CAS: 1219174-94-3

Ref. 3D-IF178225

Product Information

• Name: Fluticasone propionate EP Impurity F
• Brand: Biosynth
• Description: Fluticasone Propionate EP Impurity F is an impurity of Fluticasone Propionate. Fluticasone Propionate is a synthetic glucocorticoid used in the treatment of asthma and other allergic disorders. Impurity F is a metabolite of Fluticasone Propionate and has been detected in human plasma at low levels (5% of total fluticasone propionate). The metabolism of Fluticasone Propionate to Impurity F has been studied in rat, mouse, dog and man.br>br>The following table summarizes the metabolic pathways that have been identified for this impurity:br>br>Metabolism studies indicate that Impurity F is mainly metabolized by CYP3A4 to form conjugates with glucuronic acid or sulfates. It may also be hydrolyzed to form 5α-flurostan-3β,17β-d

Chemical properties

• Molecular weight: 498.56 g/mol
• Formula: C₂₅H₂₉F₃O₅S
• Purity: Min. 95%
• Color/Form: Powder