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(1S)-2-Acetylamino-1-(chloromethyl)ethyl acetate
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(1S)-2-Acetylamino-1-(chloromethyl)ethyl acetate

CAS: 183905-31-9

Ref. 3D-IHA90531

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Estimated delivery in United States, on Monday 8 Jul 2024

Product Information

Name:
(1S)-2-Acetylamino-1-(chloromethyl)ethyl acetate
Synonyms:
  • (S)-N-[2-(Acetyloxy)-3-chloropropyl]acetamide
  • N-[(2S)-2-(acetyloxy)-3-chloropropyl]-acetamide
  • Intermediate of Linezolid 1
  • (S)-1-[(Acetylamino)methyl]-2-chloroethyl acetate
Description:

(1S)-2-Acetylamino-1-(chloromethyl)ethyl acetate is a chemical compound that is used as an anti-infective medicine. It is synthesized by the ring opening of a pyridine with ethyl acetate and acetic acid, followed by an acylation reaction with triethylamine and acetic anhydride in the presence of aluminium chloride. The yield is high and the product can be recrystallized to give pure (1S)-2-acetylamino-1-(chloromethyl)ethyl acetate. This chemical compound has been industrialised for use in medicine and industry. The ring opening reaction releases two molecules of hydrogen chloride, which can be removed from the synthesis mixture with a Dean-Stark apparatus to yield 2-acetylamino-1-(chloromethyl)ethanol. This product can then be reacted with ethyl chloroformate to produce (1S)-

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
193.63 g/mol
Formula:
C7H12ClNO3
Purity:
Min. 95%
MDL:
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Hazard Info

UN Number:
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Forbidden to fly:
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