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Leupeptin
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Leupeptin

CAS: 103476-89-7

Ref. 3D-ILP-4041

1g
2,123.00 €
25mg
164.00 €
100mg
338.00 €
Estimated delivery in United States, on Tuesday 14 Jan 2025

Product Information

Name:
Leupeptin
Synonyms:
  • (2S)-2-(acetylamino)-N-[(2S)-2-({4-[(diaminomethylidene)amino]-1-formylbutyl}amino)-4-methylpentanoyl]-4-methylpentanamide (non-preferred name)
  • 2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide
  • <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)
  • <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, sulfate (2:1)
  • Acetyl-L-leucyl-L-leucylargininal
  • L-Leucinamide, N-acetyl-L-leucyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
  • Leupeptin Ac-LL
  • Leupeptin Hemisulfate From Microbial*Source
  • Leupeptin hemisulfate
  • N-Acetyl-L-leucyl-L-leucyl-L-argininal
  • See more synonyms
  • N-acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-L-leucinamide
  • Nk-381
  • Valeramide, 2-(2-acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methyl-
  • L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)
  • L-Leucinamide, N-acetyl-L-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, sulfate (2:1)
Description:

Leupeptin is a protease inhibitor that inhibits the activity of proteases in cells. It has been shown to inhibit transcriptional regulation and apoptosis pathway, as well as possessing anti-inflammatory properties. Leupeptin has been shown to have inhibitory properties against a variety of proteases, including group P2 metalloproteases, cathepsin D, and proteinase 3. This drug has also been shown to prevent neuronal death in experimental models by inhibiting cell lysis. Leupeptin binds to the active site of the enzyme by forming hydrogen bonds with conserved amino acid residues and steric interactions with nearby amino acid residues. The redox potentials of leupeptin are not known, but it is assumed that they are low enough for its antioxidant properties to be effective.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
475.6 g/mol
Formula:
C20H38N6O4H2SO
Purity:
Min. 90 Area-%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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