5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole

CAS: 88546-55-8

Ref. 3D-IM57926

Product Information

• Name: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole
• Synonyms: Esomeprazole magnesium trihydrate impurity DOmeprazole impurity DOmeprazole sulphone, 1H-Benzimidazole, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-, 1H-benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-, 2-[(3,5-Dimethyl-4-methoxy-2-pyridyl)methylsulfonyl]-5-methoxy-1H-benzimidazole, 5-Methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfonyl}-1H-benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulphonyl)-1H-benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethylpridin-2-yl)Methyl]sulfonyl]-1H-benzimidazole, 6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole, H 168/66, Omeprazole sulfone, Omeprazole sulphone

Description

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole is an inhibitor of cytochrome P450 2C19. It has been shown to inhibit the activity of this enzyme in a concentration dependent manner and to enhance the activity of omeprazole by inhibiting its metabolism. 5-Methoxy-2-[(4-methoxy, 3,5 dimethylpyridiniumyl)methyl]sulfonyl]-1H benzimidazole is used as a model system for studying drug interactions due to its ability to inhibit cytochrome P450 2C19 and CYP2C19 protein expression. 5 METHOXY - 2 - [[ ( 4 - METHOXY - 3 , 5 - DIMETHYL - 2 - PYRIDINYL ) M

• Brand: Biosynth

Chemical properties

• Molecular weight: 361.42 g/mol
• Formula: C₁₇H₁₉N₃O₄S
• Purity: Min. 95%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C17H19N3O4S/c1-10-8-18-15(11(2)16(10)24-4)9-25(21,22)17-19-13-6-5-12(23-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
• InChI key: InChIKey=IXEQEYRTSRFZEO-UHFFFAOYSA-N
• SMILES: COc1ccc2nc(S(=O)(=O)Cc3ncc(C)c(OC)c3C)[nH]c2c1