(3S)-3-Acetamido-4-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-3-carboxy-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-4-methyl -1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-oxobutanoic acid
CAS: 958001-92-8
Ref. 3D-INB00192
1mg | Discontinued | ||
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued | ||
50mg | Discontinued |
Product Information
(3S)-3-Acetamido-4-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-3-carboxy-1-[(4-methyl-2-oxochromen-7-yl)amino]-1 -oxopropan-2 -yl]amino]-4 -methyl -1 -oxopentan -2 -yl]amino]-1,4 -dioxobutan -2 -yl]amino]-4-oxobutanoic acid (AFQ058) is a basic protein that has been shown to have neuroprotective and apoptotic effects in animal models of Alzheimer's disease. It is also toxic to cancer cells and inhibits the proliferation of human myeloid derived suppressor cells. AFQ058 binds to histone H3, which may contribute to its regulation of transcriptional activity. This compound has been shown to