Olanzapine N-oxide
CAS: 174794-02-6
Ref. 3D-IO106348
| 5mg | 150.00 € | ||
| 10mg | 216.00 € | ||
| 25mg | 381.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 861.00 € |
Product Information
- Olanzapine impurity 4Olanzapine impurity D
- Ly 170238
- 2-Methyl-4-(4-methyl-4-oxido-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
- 2-methyl-4-(4-methyl-4-oxidopiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Olanzapine N-oxide is a metabolite of olanzapine. It is produced by the oxidative deamination of olanzapine, which is catalyzed by cytochrome P450 enzymes. Olanzapine N-oxide has been shown to be responsible for some of the side effects associated with olanzapine, such as weight gain and sedation. The presence of olanzapine N-oxide in human plasma has been shown to increase with age and in women, which may be due to its higher affinity for α1-acid glycoprotein. Olanzapine N-oxide can be detected in urine or faeces using gas chromatography/mass spectrometry (GC/MS) or liquid chromatography with tandem mass spectrometry (LC/MS).
Chemical properties
Technical inquiry about: 3D-IO106348 Olanzapine N-oxide
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