Product Information
- Benzamide, 4-[[2-[[4-[2-(4-acetyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-N-(2-chlorophenyl)-
- 4-[[2-[[4-[2-(4-Acetyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-N-(2-chlorophenyl)benzamide
Aurora A inhibitor II is a drug that inhibits the activity of Aurora A. It has been shown to inhibit tumor growth in cancer models, as well as to prevent the formation of new blood vessels (angiogenesis). Aurora A inhibitor II is being developed for the treatment of cancers, including colon carcinoma and melanoma. The drug has also been shown to inhibit bile acid transport, which may be responsible for its antitumor activity. This drug binds to regulatory proteins and growth factors, blocking their interactions with target molecules, which leads to inhibition of cell growth and proliferation. Aurora A inhibitor II has also been shown to bind to human colon carcinomas in vitro and in vivo.
Chemical properties
Technical inquiry about: 3D-IWB83843 Aurora A inhibitor II
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