5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

CAS: 23256-42-0

Ref. 3D-J-516148

Product Information

• Name: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
• Synonyms: 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine lactate Trimethoprim lactic acid Trimethoprim lactate, 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Lactate salt, 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine lactate, 2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]-, mono(2-hydroxypropanoate), 2-Hydroxypropanoic Acid - 5-(3,4,5-Trimethoxybenzyl)Pyrimidine-2,4-Diamine (1:1), Lactic acid, compd. with 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine (1:1), Lactotrim, Propanoic acid, 2-hydroxy-, compd. with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine (1:1), Trimethoprim lactate salt

Description

5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate is an antibacterial compound with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. It is active against strains resistant to other antibiotics, such as, tetracycline and penicillin. 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate has been shown to be effective in vitro against Campylobacter jejuni - the most common cause of bacterial gastroenteritis in humans. The compound also inhibits the growth cycle of Campylobacter jejuni by arresting the cells at the G1 phase. The molecule has been shown to inhibit DNA synthesis in E. coli and S. typhimurium with IC50 values of 1 ÎŒM and 0.8 ÎŒM respectively. This molecule has been tested for its surface active properties and it can be used as an additive in personal care products for improved wetting and spreading on surfaces. The compound is also researched for its antifungal efficacy against Candida albicans by inhibiting the growth cycle of the fungus.

• Brand: Biosynth

Chemical properties

• Molecular weight: 380.40 g/mol
• Formula: C₁₇H₂₄N₄O₆
• Purity: Min. 98 Area-%