Chloramphenicol acetyltransferase from escherichia coli
CAS: 9040-07-7
Ref. 3D-JAA04007
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Chloramphenicol acetyltransferase is an enzyme that catalyzes the acetylation of chloramphenicol to form chloramphenicol acetate. This enzyme is a member of the family of acetyltransferases and is encoded by the cat gene. It has been found in several organisms, including Escherichia coli K-12, Saccharomyces cerevisiae, and Bacillus subtilis. Chloramphenicol acetyltransferase catalyzes the conversion of chloramphenicol to chloramphenicol acetate by transferring an acetyl group from coenzyme A to the drug molecule. The crystal structure of this enzyme has been determined at 1.7 Å resolution and reveals an α/β protein fold with a single domain organization.
Chemical properties
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