Rocaglamide
CAS: 84573-16-0
Ref. 3D-JDA57316
1mg | Discontinued | ||
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued | ||
50mg | Discontinued |
Product Information
- 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, [1R-(1α,2α,3β,3aβ,8bβ)]-
- NSC 326408
- (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide
- 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-
Rocaglamide is a synthetic compound that inhibits the mitochondrial membrane potential and induces apoptosis pathways. This compound also has potent antitumor activity in vivo, which may be due to its ability to inhibit the synthesis of DNA, RNA and protein in tumor cells. Rocaglamide inhibits cancer cells by inhibiting the production of ATP, which leads to cell death through necrosis or apoptosis. The hydroxyl group on rocaglamide's structure is thought to be responsible for its antitumor activity.