2-Chloro-5-hydrazinylbenzoic acid hydrochloride
CAS: 184163-49-3
Ref. 3D-JHA16349
| 1g | 691.00 € | ||
| 10g | 2,429.00 € |
Product Information
2-Chloro-5-hydrazinylbenzoic acid hydrochloride (CHB) is a costimulatory molecule that activates the immune system. It binds to the receptor CTLA-4 and prevents it from binding to its ligand, B7. This prevents the inhibitory signal from being transmitted to T cells and leads to an increase in immune responses. CHB has been shown to be effective in treating bladder cancer as well as other cancer types such as colorectal cancer and esophageal cancer. In addition, this drug has anti-inflammatory effects, which can be attributed to its ability to activate monocytes and macrophages, leading to production of cytokines such as IL-1β and IL-6.
Chemical properties
Technical inquiry about: 3D-JHA16349 2-Chloro-5-hydrazinylbenzoic acid hydrochloride
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