Product Information
U-99194-d6 Maleate Salt is a cell adhesion molecule that is expressed in the brain and has been shown to be a marker of stem cells. It has been shown in a rat model to have clinical relevance for Parkinson’s disease by regulating dopamine levels. U-99194-d6 Maleate Salt regulates the energy metabolism of dopaminergic neurons, which are involved in the regulation of voluntary movement and cognition. This compound binds to dopamine D2 receptors, which are involved in locomotor activity and striatal dopamine release, as well as quinpirole binding sites, which are involved in the regulation of mood.
U-99194-d6 Maleate Salt also influences dopamine levels through its expression in hippocampal formation, an area of the brain that is involved with memory. In vitro assays have shown that this compound inhibits proliferation and migration of neural progenitor cells (NPCs) by inhibiting receptor signaling pathways downstream from β1
Chemical properties
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