Product Information
- Furegrelate
- 5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium
- Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate
- U 63557A
- 2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-, sodium salt
- Sodium 5-(Pyridin-3-Ylmethyl)-1-Benzofuran-2-Carboxylate
Furegrelate is a prodrug that undergoes enzymatic biotransformation to its active form, furogrelate. Furogrelate is an inhibitor of angiogenesis, which is the growth of new blood vessels from pre-existing ones. Furogrelate inhibits the 2 enzymes required for the synthesis of fumarate and succinate, which are key intermediates in the biosynthesis of fatty acids. This inhibition leads to a decrease in fatty acid production and in turn, decreases formation of new blood vessels. Furogrelate also has anti-inflammatory properties and has been shown to inhibit tumor growth in experimental cancer models.
Chemical properties
Technical inquiry about: 3D-KDA66617 Furegrelate sdium
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