CGS 19755

CAS: 110347-85-8

Ref. 3D-KEA34785

Product Information

• Name: CGS 19755
• Synonyms: (2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid, 2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, (2R,4S)-rel-, 2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, cis-, Cgs 19755, Cpdd 0027, Selfotel [USAN:INN], cis-4-(Phosphonomethyl)pipecolic acid, cis-4-[Phosphonomethyl]-2-piperidinecarboxylic acid, rel-(2R,4S)-4-(Phosphonomethyl)-2-piperidinecarboxylic acid
• CAS: 110347-85-8

Description

CGS 19755 is a low-potency compound that has been investigated for its potential use in the treatment of neurodegenerative diseases. It is a selective, non-competitive antagonist of the metabotropic glutamate receptor type 2 (mGluR2) which has shown to reduce neuronal death and improve motor function in experimental models. CGS 19755 has also been shown to have no significant side-effect profiles in humans and has been tested as a pharmacological agent for the treatment of Parkinson's disease. The major analytical method used to measure the potency of CGS 19755 is intracellular Ca2+ levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 223.17 g/mol
• Formula: C₇H₁₄NO₅P
• Purity: Min. 95%