Product Information
Pandinotoxin-kα is a synthetic glucocorticoid that binds to the glucocorticoid receptor and blocks ion channels. It has been shown to have cytostatic and cytotoxic properties on cancer cells. Pandinotoxin-kα also has a reversible effect on conductances, which are channels in cell membranes that help to regulate the passage of ions and other molecules into and out of cells. This drug is currently being studied for its potential use as an antineoplastic agent. Pandinotoxin-kα is a type of constant blocker, which means it inhibits the movement of potassium ions through channels in the membrane of cells.
The drug was developed by modifying the natural compound pandinotoxin with an alpha-subunit that was synthetically derived from glibenclamide, a drug used to treat type 2 diabetes mellitus.
Chemical properties
Technical inquiry about: 3D-KHA52964 Pandinotoxin-kα
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