PDGFR Tyrosine Kinase Inhibitor VI, SU6668

CAS: 210644-62-5

Ref. 3D-KIA64462

Product Information

• Name: PDGFR Tyrosine Kinase Inhibitor VI, SU6668
• Synonyms: 1H-Pyrrole-3-propanoic acid, 5-((1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-, 1H-Pyrrole-3-propanoic acid, 5-[(Z)-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, 3-(2,4-Dimethyl-5-((2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-1H-pyrrol-3-yl)propionic acid, 3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid, 5-((1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-propanoic acid
• CAS: 210644-62-5

Description

PDGFR Tyrosine Kinase Inhibitor VI (SU6668) is a chemical compound that inhibits the tyrosine kinase domain of the PDGFR. It has been shown to be effective in treating metastatic colorectal cancer, and has been approved for use in Japan. Due to its toxicity profile, SU6668 cannot be used for long periods of time. The most common side effects are diarrhea, nausea, vomiting, neutropenia, and anemia. The toxicities observed in animal studies include weight loss, hemoptysis, thrombocytopenia, alopecia, hepatotoxicity and myelosuppression.

• Brand: Biosynth

Chemical properties

• Molecular weight: 310.35 g/mol
• Formula: C₁₈H₁₈N₂O₃
• Purity: Min. 95%