Product Information
- 163M
- 20208Xpa
- 20209Xpb
- 20Lar
- 315Hvx
- 4051Ep
- 4052Ep
- 4054Ep
- 8586B
- ACM
- See more synonyms
- Acr107
- Aem-G
- Aem-Gls
- Aem-Gxf
- Aem-Gxf-M
- Ar100
- Aresugomutekkusu
- Bnef
- Durastrength400R
- EAKKh
- H660
- Ht-Acm-Ex
- Ht-Acm-Exao
- Ht-Acm-M
- Ht-Acm-Mao
- Hycar2600H
- Hycar4000Z
- Hycar4041CG
AR-42 is a non-radioactive compound that was originally developed by the U.S. Department of Defense for use as an incapacitating agent, but it has also been studied for use as a cancer drug. AR-42 increases the mitochondrial membrane potential in tumor cells and inhibits their growth in vitro. AR-42 has also been shown to inhibit leukemia inhibitory factor (LIF), which suppresses the immune system and prevents the body from attacking tumors. AR-42 is metabolized into 2 molecules of carbon dioxide and one molecule of water, so it does not have any toxic effects on healthy cells.
AR-42 is a mitochondria-targeting drug that causes increased mitochondrial membrane potential in tumor cells and inhibits their growth in vitro. It has also been shown to inhibit leukemia inhibitory factor (LIF), which suppresses the immune system and prevents the body from attacking tumors. AR-42 is metabolized into 2 molecules of carbon dioxide and one molecule of water, so
Chemical properties
Technical inquiry about: 3D-KMB88137 AR-42
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