3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-one
CAS: 36822-08-9
Ref. 3D-LBA82208
1g | To inquire | |
5g | To inquire | |
10g | To inquire | |
250mg | To inquire | |
500mg | To inquire |
Product Information
3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-one is a small molecule that is a potent antagonist of the WNT/β-catenin signaling pathway. It binds to the ATP binding site on the β-catenin protein and prevents it from interacting with TCF/LEF transcription factors, which prevents gene expression. 3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-one has been shown to inhibit cancer cell growth in vitro and in vivo. This drug also has anticancer activity against breast cancer cells by inhibiting proliferation and inducing apoptosis.
Chemical properties
Technical inquiry about: 3D-LBA82208 3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-one
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