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GSK 2193874
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GSK 2193874

CAS: 1336960-13-4

Ref. 3D-LDC96013

5mg
146.00 €
10mg
210.00 €
25mg
369.00 €
50mg
492.00 €
100mg
656.00 €
Estimated delivery in United States, on Thursday 11 Jul 2024

Product Information

Name:
GSK 2193874
Description:

GSK2193874 is a potent and selective small molecule for the treatment of chronic cough. It inhibits the activation of TRPV4, which is a member of the transient receptor potential cation channel family, in primary cells by pharmacological agents and in vitro by intracellular Ca2+ levels. GSK2193874 has been shown to inhibit acetylcholinesterase activity and to increase cytosolic calcium levels in atrial myocytes. This drug also has effects on congestive heart failure (CHF) patients, such as an increase in left ventricular function and improved pulmonary hemodynamics. GSK2193874 also binds to toll-like receptor 4 (TLR4), which may be a therapeutic target for the treatment of chronic cough.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
691.62 g/mol
Formula:
C37H38BrF3N4O
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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