1-Benzyl-4-methylpiperazine dihydrochloride
CAS: 861020-53-3
Ref. 3D-LJB02053
| 2g | 136.00 € | ||
| 5g | 205.00 € | ||
| 10g | 307.00 € | ||
| 25g | 534.00 € | ||
| 50g | 814.00 € |
Product Information
1-Benzyl-4-methylpiperazine dihydrochloride (1BMP) is a structural analog of imatinib, which is an allosteric inhibitor of the enzyme b-raf. 1BMP binds to the ATP binding site on b-raf and prevents it from activating its target protein, the kinase enzyme that plays a key role in cell division. Imatinib has been shown to be effective in treating chronic myeloid leukemia and other cancers with mutations in the b-raf gene. Sorafenib, another allosteric inhibitor of b-raf, was also found to be effective against chronic myeloid leukemia, as well as pancreatic cancer and hepatocellular carcinoma.
Chemical properties
Technical inquiry about: 3D-LJB02053 1-Benzyl-4-methylpiperazine dihydrochloride
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