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5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one
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5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one

CAS: 311795-38-7

Ref. 3D-LMA79538

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Estimated delivery in United States, on Wednesday 8 Jan 2025

Product Information

Name:
5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one
Description:

5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one (TZT) is an experimental drug that inhibits glutaminase and is used to treat cancer. It has been shown to inhibit the growth of human epidermal growth factor receptor 2 (HER2), mda-mb231 breast cancer cells and human CD4+ lymphocytes. TZT also inhibits the production of glutamine in cancer cells. This inhibition leads to a decrease in the synthesis of proteins and DNA, which may lead to apoptosis or cell death. TZT has been shown to be effective against a number of carcinoma cell lines including cervical cancer and is not toxic for normal cells such as fetal bovine serum or healthy skin fibroblasts.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
475.42 g/mol
Formula:
C27H27BrN2O
Purity:
Min. 95%
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Hazard Info

UN Number:
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