![5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide](https://static.cymitquimica.com/products/3D/img/LXB65151.png "Click to enlarge")
5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS: 1186651-51-3
Ref. 3D-LXB65151
| 2mg | 136.00 € | ||
| 5mg | 194.00 € | ||
| 10mg | 310.00 € | ||
| 25mg | 453.00 € | ||
| 50mg | 712.00 € |
Product Information
Imatinib is a tyrosine kinase inhibitor that inhibits the activity of ATP-binding cassette subfamily B member 1, a protein involved in the regulation of cellular proliferation and differentiation. Imatinib binds to the ATP-binding site and blocks access to ATP, preventing the generation of phosphorylation, which is necessary for DNA synthesis and cell division. Imatinib has been shown to be effective against chronic myeloid leukemia (CML) by inhibiting the activity of the bcr-abl protein. However, imatinib also inhibits other proteins that are not associated with cancer, such as stem cell factor and cell factor. This drug has been shown to have potential for repositioning in cancer therapy due to its ability to inhibit growth factors that promote tumorigenesis.
Chemical properties
Technical inquiry about: 3D-LXB65151 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
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