N-Acetyl-D-mannosamine

CAS: 7772-94-3

Ref. 3D-MA05269

Product Information

• Name: N-Acetyl-D-mannosamine
• Synonyms: 2-Acetamido-2-deoxy-D-mannopyranose N-Acetyl-D-mannosaminide, 2-(Acetylamino)-2-Deoxyhexopyranose Hydrate, 2-(Acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</span>-mannopyranose, 2-(acetylamino)-2-deoxy-alpha-D-gulopyranose, Mannopyranose, 2-acetamido-2-deoxy-, β-<span class="text-smallcaps">D</span>-, N-Acetyl-D-mannosamine monohydrate, β-<span class="text-smallcaps">D</span>-Mannopyranose, 2-(acetylamino)-2-deoxy-
• CAS: 7772-94-3

Description

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

• Brand: Biosynth

Chemical properties

• Molecular weight: 221.21 g/mol
• Formula: C₈H₁₅NO₆
• Purity: Min. 98 Area-%
• Color/Form: White Powder