N-Acetyl-9-azido-9-deoxy-neuraminic acid
CAS: 76487-51-9
Ref. 3D-MA30919
| 2mg | 194.00 € | ||
| 5mg | 313.00 € | ||
| 10mg | 459.00 € | ||
| 25mg | 746.00 € | ||
| 50mg | 1,219.00 € |
Product Information
- 5-(Acetylamino)-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-2-nonulosonic acid9-Azido-N-acetylneuraminic acid
N-Acetyl-9-azido-9-deoxy-neuraminic acid is used as a sialic acid substitute for metabolic glycan labelling, which allows glycan-protein interactions and sialylations to be interrogated. Naturally occurring glycans can be di-sialylated by sialidase and replaced by a sialyl analogue, such as N-acetyl-9-azido-9-deoxy-neuraminic acid, using sialyltransferase. The modified glycans are then resistant to sialidase. Reduction of the azide functionality of N-acetyl-9-azido-9-deoxy-neuraminic acid affords access to an additional 9-amino sialic acid analogue which can be further elaborated to 9-amido analogues.
Glycans labelled with N-acetyl-9-azido-9-deoxy-neuraminic acid can be tagged and imaged by reaction of the 9-azido group with, for example, a fluorescent tag introduced via a Staudinger ligation.
Chemical properties
Technical inquiry about: 3D-MA30919 N-Acetyl-9-azido-9-deoxy-neuraminic acid
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