N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate

CAS: 53678-77-6

Ref. 3D-MA58738

Product Information

• Name: N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate
• Synonyms: N-Ac-Mur-Ala-D-Glu-NH2N-Acetylmuramyl-L-Ala-D-Glu-NH2Muramyl dipeptideAdjuvant peptide, (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name), (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,5S)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name), 2: PN: WO2009039971 PAGE: 99 claimed protein, <span class="text-smallcaps">D</smallcap>-α-Glutamine, N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl-, <span class="text-smallcaps">D</smallcap>-α-Glutamine, N²-[N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl]-, Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine, Acetylmuramyl-L-alanyl-D-isoglutamine, Acetylmuramyl-alanyl-isoglutamine, Brn 4220745, D-alpha-Glutamine, N(sup 2)-(N-(N-acetylmuramoyl)-L-alanyl)-, D-alpha-Glutamine, N2-(N-(N-acetylmuramoyl)-L-alanyl)-, D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-, D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-, MDP, MDP-<span class="text-smallcaps">D</span>, Muramoyl dipeptide, Muramyl dipeptide, N(sup 2)-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine, N-(Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine, N-(Acetylmuramoyl)alanyl-<span class="text-smallcaps">D</span>-isoglutamine, N-(Acetylmuramoyl)alanyl-D-isoglutamine, N-(N-Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-α-glutamine, N-Acetylmuramoyl dipeptide, N-Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanine-<smallcap>D</span>-isoGln, N-Acetylmuramoylalanyl-<span class="text-smallcaps">D</span>-isoglutamine, N-Acetylmuramyl dipeptide, N-Acetylmuramyl-L-Alanyl-D-Isoglutamine, N-Acetylmuramyl-L-alanine-D-isoGln, N2-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine, N2-[N-(N-Acetylmuramoyl)-L-alanyl]-D-α-glutamin, N2-[N-(N-acetilmuramoil)-L-alanil]-D-α-glutamina

Description

Muramyl dipeptide is a component of the bacterial cell wall and is found in mycobacteria, mycoplasmas, spirochetes, and gram-positive bacteria. Muramyl dipeptide has been shown to induce the activation of macrophages and other cells by stimulating toll-like receptor 4. It also has significant cytotoxicity against various cancer cells, as well as potent inducers of ubiquitin ligases. The use of muramyl dipeptide in vitro was shown to inhibit replication of HIV-1 virus in human lymphocytes. This agent has also been used for the treatment of bowel disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 492.48 g/mol
• Formula: C₁₉H₃₂N₄O₁₁·xH₂O
• Purity: Min. 96 Area-%
• Color/Form: Powder