8-(Benzyloxy)guanosine

CAS: 3868-36-8

Ref. 3D-MB16633

Product Information

• Name: 8-(Benzyloxy)guanosine
• Synonyms: 8-(Phenylmethoxy)guanosineNSC 90391, 2-Amino-8-(benzyloxy)-9-pentofuranosyl-1,9-dihydro-6H-purin-6-one, 6H-purin-6-one, 2-amino-1,9-dihydro-9-pentofuranosyl-8-(phenylmethoxy)-, 2-amino-8-(benzyloxy)-9-pentofuranosyl-3,9-dihydro-6H-purin-6-one

Description

8-(Benzyloxy)guanosine is a novel nucleoside analog that is an activator of ribonucleotide reductase. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo, as well as inhibit the production of diphosphate from ATP. This compound also has antiviral activity against herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1). 8-(Benzyloxy)guanosine is synthesized by reacting the 8-hydroxy group on guanosine with benzaldehyde, followed by phosphorylation with diphosphate. This compound has CAS No. 3868-36-8 and can be used for research purposes only.

• Brand: Biosynth

Chemical properties

• Molecular weight: 389.36 g/mol
• Formula: C₁₇H₁₉N₅O₆
• Purity: Min. 95 Area-%
• Color/Form: White To Off-White Solid
• InChI: InChI=1S/C17H19N5O6/c18-16-20-13-10(14(26)21-16)19-17(27-7-8-4-2-1-3-5-8)22(13)15-12(25)11(24)9(6-23)28-15/h1-5,9,11-12,15,23-25H,6-7H2,(H3,18,20,21,26)/t9-,11-,12-,15-/m1/s1
• InChI key: InChIKey=RNSGUQLXDMZREX-SDBHATRESA-N
• SMILES: Nc1nc2c(nc(OCc3ccccc3)n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1