Product Information
MPO-IN-28 is a specific inhibitor of myeloperoxidase (MPO) and has shown to be efficacious in the treatment of inflammatory diseases. MPO-IN-28 is a reactive, microbicidal compound that inhibits MPO by binding to its catalytic site and blocking its activity. MPO-IN-28 has shown IC50 values of 0.5 μM for myeloperoxidase inhibition. This inhibition was confirmed by pharmacophore modeling, which predicted that the active form of MPO-IN-28 would bind to the catalytic site of MPO with an affinity constant of 2 nM.
Chemical properties
Technical inquiry about: 3D-MBA83690 MPO-IN-28
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