Product Information
- 4-((4H-1,2,4-Triazol-4-Yl)Methyl)Benzonitrile
- 4-(1,2,4-Triazol-4-Ylmethyl)Benzonitrile
- 1-(4-Cyanobenzyl)-1,3,4-triazole
4-(4-Cyanobenzyl)-1,2,4-triazole is a synthetic compound that has been used as an inhibitor of the bacterial enzyme dihydrofolate reductase (DHFR). It is a structural analog of methotrexate and thus binds to the active site of DHFR. The 4-cyanobenzyl group occupies the position of the 4-amino group in methotrexate, which is important for binding to DHFR.
Chemical properties
Technical inquiry about: 3D-MEA80927 4-(4-Cyanobenzyl)-1,2,4-triazole
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