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Cis-atovaquone
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Cis-atovaquone

CAS: 137732-39-9

Ref. 3D-MFA73239

1mg
108.00 €
5mg
260.00 €
10mg
407.00 €
25mg
543.00 €
50mg
759.00 €
Estimated delivery in United States, on Tuesday 16 Jul 2024

Product Information

Name:
Cis-atovaquone
Description:

Cis-atovaquone is an effective drug that inhibits the growth of Plasmodium falciparum, a parasite responsible for malaria. It works by binding to the cytochrome bc1 complex in the mitochondrial electron transport chain and disrupting the production of ATP, which is essential for DNA synthesis and protein production. Cis-atovaquone has been shown to have a strong inhibitory effect on liver mitochondria and has high catalytic efficiency. Molecular docking studies suggest that it binds to the active site of the enzyme and forms intermolecular interactions such as hydrogen bonds with amino acid residues. Crystal structures of the protein-inhibitor complex provide insights into its mechanism of action. In control mice, Cis-atovaquone has been shown to be highly effective against malaria infections, making it a promising candidate for future treatments.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
366.8 g/mol
Formula:
C22H19ClO3
Purity:
Min. 95%
MDL:
Melting point:
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Flash point:
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Concentration:
EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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